Phenylbutyrate, a histone deacetylase inhibitor, protects against Adriamycin-induced cardiac injury

Phenylbutyrate, a histone deacetylase inhibitor, protects against Adriamycin-induced cardiac injury

Cardiac injury is a major complication for oxidative-stress-generating anticancer agents exemplified by Adriamycin (ADR). Recently, several histone deacetylase inhibitors (HDACIs) including phenylbutyrate (PBA) have shown promise in the treatment of cancer with little known toxicity to normal tissue...

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Bibliographic Details
Main Authors: Chotiros Daosukho, Yumin Chen, Teresa Noel, Pradoldej Sompol, Ramaneeya Nithipongvanitch, Joyce M. Velez, Terry D. Oberley, Daret K. St. Clair
Other Authors: University of Kentucky College of Medicine
Format: Article
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/24182
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/24182

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