Phenylbutyrate, a histone deacetylase inhibitor, protects against Adriamycin-induced cardiac injury
Cardiac injury is a major complication for oxidative-stress-generating anticancer agents exemplified by Adriamycin (ADR). Recently, several histone deacetylase inhibitors (HDACIs) including phenylbutyrate (PBA) have shown promise in the treatment of cancer with little known toxicity to normal tissue...
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Main Authors: | , , , , , , , |
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Format: | Article |
Published: |
2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/24182 |
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Institution: | Mahidol University |