Comparison of prevention of NSAID-induced gastrointestinal complications by rebamipide and misoprostol: A randomized, multicenter, controlled trial - STORM study

• Main Authors: Soo Heon Park, Chul Soo Cho, Oh Young Lee, Jae Bum Jun, San Ren Lin, Li Ya Zhou, Yao Zong Yuan, Zhao Shen Li, Xiao Hua Hou, Hong Chuan Zhao, Udom Kachintorn, Chomsri Kositchaiwat, Comson Lertkupinit
• Other Authors: The Catholic University of Korea
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine; Nursing
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/24244
• Institution: Mahidol University

Nonsteroidal anti-inflammatory drugs (NSAIDs) have gastrointestinal side effects such as dyspepsia, peptic ulcer, hemorrhage, and perforation. Misoprostol and PPIs have been used to prevent NSAID-induced gastroduodenal injury. Rebamipide increases gastric mucus and stimulates the production of endog...