How much fat is necessary to optimize lumefantrine oral bioavailability?

How much fat is necessary to optimize lumefantrine oral bioavailability?

Background: Artemether-lumefantrine (AL) is the only fixed, artemisinin-based combination antimalarial drug which is registered internationally and deployed on a large scale. Absorption of the hydrophobic lipophilic lumefantrine component varies widely between individuals and is greatly increased by...

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Bibliographic Details
Main Authors: Elizabeth A. Ashley, Kasia Stepniewska, Niklas Lindegårdh, Anna Annerberg, Am Kham, Al Brockman, Pratap Singhasivanon, Nicholas J. White, François Nosten
Other Authors: Shoklo Malaria Research Unit
Format: Article
Published: 2018
Subjects:
Immunology and Microbiology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/24590
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/24590

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