Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites

• Main Authors: Mallika Imwong, Georges Snounou, Sasithon Pukrittayakamee, Naowarat Tanomsing, Ryong Kim Jung, Amitab Nandy, Jean Paul Guthmann, Francois Nosten, Jane Carlton, Sornchai Looareesuwan, Shalini Nair, Daniel Sudimack, Nicholas P.J. Day, Timothy J.C. Anderson, Nicholas J. White
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/24939

Background. Relapses originating from hypnozoites are characteristic of Plasmodium vivax infections. Thus, reappearance of parasitemia after treatment can result from relapse, recrudescence, or reinfection. It has been assumed that parasites causing relapse would be a subset of the parasites that ca...