Are transporter genes other than the chloroquine resistance locus (pfcrt) and multidrug resistance gene (pfmdr) associated with antimalarial drug resistance?

by Timothy J C Anderson, Shalini Nair, Huang Qin, Sittaporn Singlam, Alan Brockman, Lucy Paiphun, François Nosten
Published 2018

Pooled sequencing and rare variant association tests for identifying the determinants of emerging drug resistance in malaria parasites

by Ian H. Cheeseman, Marina McDew-White, Aung Pyae Phyo, Kanlaya Sriprawat, Francois Nosten, Timothy J.C. Anderson
Published 2018

Single-genome sequencing reveals within-host evolution of human malaria parasites

by Aliou Dia, Catherine Jett, Simon G. Trevino, Cindy S. Chu, Kanlaya Sriprawat, Timothy J.C. Anderson, François Nosten, Ian H. Cheeseman
Published 2022

Single-cell genomics for dissection of complex malaria infections

by Shalini Nair, Standwell C. Nkhoma, David Serre, Peter A. Zimmerman, Karla Gorena, Benjamin J. Daniel, Francxois Nosten, Timothy J.C. Anderson, Ian H. Cheeseman
Published 2018

Gene amplification of the multidrug resistance 1 gene of Plasmodium vivax isolates from Thailand, Laos, and Myanmar

by Mallika Imwong, Sasithon Pukrittayakamee, Wirichada Pongtavornpinyo, Supatchara Nakeesathit, Shalini Nair, Paul Newton, Francois Nosten, Timothy J.C. Anderson, Arjen Dondorp, Nicholas P.J. Day, Nicholas J. White
Published 2018

Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent

by Aimee R. Taylor, Stephen F. Schaffner, Gustavo C. Cerqueira, Standwell C. Nkhoma, Timothy J.C. Anderson, Kanlaya Sriprawat, Aung Pyae Phyo, François Nosten, Daniel E. Neafsey, Caroline O. Buckee
Published 2018

Population parameters underlying an ongoing soft sweep in southeast asian malaria parasites

by Timothy J.C. Anderson, Shalini Nair, Marina McDew-White, Ian H. Cheeseman, Standwell Nkhoma, Fatma Bilgic, Rose McGready, Elizabeth Ashley, Aung Pyae Phyo, Nicholas J. White, Francois Nosten
Published 2018

Pairwise growth competitions identify relative fitness relationships among artemisinin resistant Plasmodium falciparum field isolates

by Abigail R. Tirrell, Katelyn M. Vendrely, Lisa A. Checkley, Sage Z. Davis, Marina McDew-White, Ian H. Cheeseman, Ashley M. Vaughan, François H. Nosten, Timothy J.C. Anderson, Michael T. Ferdig
Published 2020

Plasmodium falciparum genetic crosses in a humanized mouse model

by Ashley M. Vaughan, Richard S. Pinapati, Ian H. Cheeseman, Nelly Camargo, Matthew Fishbaugher, Lisa A. Checkley, Shalini Nair, Carolyn A. Hutyra, François H. Nosten, Timothy J.C. Anderson, Michael T. Ferdig, Stefan H.I. Kappe
Published 2018

Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance

by Gustavo C. Cerqueira, Ian H. Cheeseman, Steve F. Schaffner, Shalini Nair, Marina McDew-White, Aung Pyae Phyo, Elizabeth A. Ashley, Alexandre Melnikov, Peter Rogov, Bruce W. Birren, François Nosten, Timothy J.C. Anderson, Daniel E. Neafsey
Published 2018

Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites

by Mallika Imwong, Georges Snounou, Sasithon Pukrittayakamee, Naowarat Tanomsing, Ryong Kim Jung, Amitab Nandy, Jean Paul Guthmann, Francois Nosten, Jane Carlton, Sornchai Looareesuwan, Shalini Nair, Daniel Sudimack, Nicholas P.J. Day, Timothy J.C. Anderson, Nicholas J. White
Published 2018

The extended recovery ring-stage survival assay provides a superior association with patient clearance half-life and increases throughput

by Sage Z. Davis, Puspendra P. Singh, Katelyn M. Vendrely, Douglas A. Shoue, Lisa A. Checkley, Marina McDew-White, Katrina A. Button-Simons, Zione Cassady, MacKenzie A.C. Sievert, Gabriel J. Foster, François H. Nosten, Timothy J.C. Anderson, Michael T. Ferdig
Published 2020

The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice

by Katrina A. Button-Simons, Sudhir Kumar, Nelly Carmago, Meseret T. Haile, Catherine Jett, Lisa A. Checkley, Spencer Y. Kennedy, Richard S. Pinapati, Douglas A. Shoue, Marina McDew-White, Xue Li, François H. Nosten, Stefan H. Kappe, Timothy J.C. Anderson, Jeanne Romero-Severson, Michael T. Ferdig, Scott J. Emrich, Ashley M. Vaughan, Ian H. Cheeseman
Published 2022

Leveraging crowdsourcing to accelerate global health solutions

by Sage Davis, Katrina Button-Simons, Taoufik Bensellak, Eren Mehmet Ahsen, Lisa Checkley, Gabriel J. Foster, Xinzhuan Su, Ahmed Moussa, Darlington Mapiye, Sok Kean Khoo, Francois Nosten, Timothy J.C. Anderson, Katelyn Vendrely, Julie Bletz, Thomas Yu, Sumir Panji, Amel Ghouila, Nicola Mulder, Thea Norman, Steven Kern, Pablo Meyer, Gustavo Stolovitzky, Michael T. Ferdig, Geoffrey H. Siwo
Published 2020

A major genome region underlying artemisinin resistance in malaria

by Ian H. Cheeseman, Becky A. Miller, Shalini Nair, Standwell Nkhoma, Asako Tan, John C. Tan, Salma Al Saai, Aung Pyae Phyo, Carit Ler Moo, Khin Maung Lwin, Rose McGready, Elizabeth Ashley, Mallika Imwong, Kasia Stepniewska, Poravuth Yi, Arjen M. Dondorp, Mayfong Mayxay, Paul N. Newton, Nicholas J. White, François Nosten, Michael T. Ferdig, Timothy J.C. Anderson
Published 2018

Plasmodium falciparum k13 mutations in africa and asia impact artemisinin resistance and parasite fitness

by Barbara H. Stokes, Satish K. Dhingra, Kelly Rubiano, Sachel Mok, Judith Straimer, Nina F. Gnädig, Ioanna Deni, Kyra A. Schindler, Jade R. Bath, Kurt E. Ward, Josefine Striepen, Tomas Yeo, Leila S. Ross, Eric Legrand, Frédéric Ariey, Clark H. Cunningham, Issa M. Souleymane, Adama Gansané, Romaric Nzoumbou-Boko, Claudette Ndayikunda, Abdunoor M. Kabanywanyi, Aline Uwimana, Samuel J. Smith, Olimatou Kolley, Mathieu Ndounga, Marian Warsame, Rithea Leang, François Nosten, Timothy J.C. Anderson, Philip J. Rosenthal, Didier Ménard, David A. Fidock
Published 2022