Plasmodium falciparum genetic crosses in a humanized mouse model

• Main Authors: Ashley M. Vaughan, Richard S. Pinapati, Ian H. Cheeseman, Nelly Camargo, Matthew Fishbaugher, Lisa A. Checkley, Shalini Nair, Carolyn A. Hutyra, François H. Nosten, Timothy J.C. Anderson, Michael T. Ferdig, Stefan H.I. Kappe
• Other Authors: Biomedical Research Institute
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/35432
• Institution: Mahidol University

© 2015 Nature America, Inc. All rights reserved. Genetic crosses of phenotypically distinct strains of the human malaria parasite Plasmodium falciparum are a powerful tool for identifying genes controlling drug resistance and other key phenotypes. Previous studies relied on the isolation of recombin...