Oral versus intravenous flucytosine in patients with human immunodeficiency virus-associated cryptococcal meningitis

• Main Authors: Annemarie E. Brouwer, Hendrikus J M Van Kan, Elizabeth Johnson, Adul Rajanuwong, Prapit Teparrukkul, Vannaporn Wuthiekanun, Wirongrong Chierakul, Nick Day, Thomas S. Harrison
• Other Authors: St George's University of London
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/24983
• Institution: Mahidol University

In a randomized controlled trial of amphotericin B-based therapy for human immunodeficiency virus (HIV)-associated cryptococcal meningitis in Thailand, we also compared the mycological efficacy, toxicity, and pharmacokinetics of oral versus intravenous flucytosine at 100 mg/kg of body weight/day for...