Loss of control of asthma following inhaled corticosteroid withdrawal is associated with increased sputum interleukin-8 and neutrophils

Background: The role of neutrophils in exacerbations of asthma is poorly understood. We examined the effect of withdrawal of inhaled corticosteroids on sputum inflammatory indexes in a double-blind study in patients with moderate, stable asthma. Methods: Following a 2-week run in period, 24 subjects...

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Bibliographic Details
Main Authors: Kittipong Maneechotesuwan, Sarah Essilfie-Quaye, Sergei A. Kharitonov, Ian M. Adcock, Peter J. Barnes
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/25044
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Institution: Mahidol University