Charged residue screening in helix 4 of the Bacillus thuringiensis Cry4B toxin reveals one critical residue for larvicidal activity

The different Cry δ-endotoxins produced by Bacillus thuringiensis have been shown to kill susceptible insect larvae by forming a lytic pore in the target midgut epithelial cell membrane. We have previously employed single proline substitutions via PCR-based mutagenesis and demonstrated that helices...

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Bibliographic Details
Main Authors: Issara Sramala, Somphob Leetacheewa, Chartchai Krittanai, Gerd Katzenmeier, Sakol Panyim, Chanan Angsuthanasombat
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/26428
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Institution: Mahidol University