Charged residue screening in helix 4 of the Bacillus thuringiensis Cry4B toxin reveals one critical residue for larvicidal activity
The different Cry δ-endotoxins produced by Bacillus thuringiensis have been shown to kill susceptible insect larvae by forming a lytic pore in the target midgut epithelial cell membrane. We have previously employed single proline substitutions via PCR-based mutagenesis and demonstrated that helices...
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Main Authors: | , , , , , |
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Format: | Article |
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2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/26428 |
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Institution: | Mahidol University |