Antimalarial halorosellinic acid from the marine fungus Halorosellinia oceanica

• Main Authors: Maneekarn Chinworrungsee, Prasat Kittakoop, Masahiko Isaka, Amporn Rungrod, Morakot Tanticharoen, Yodhathai Thebtaranonth
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/26454

Three known compounds, 2-hexylidene-3-methylsuccinic acid (1), cytochalasin Q (2), and 5-carboxymellein (3), together with two new derivatives, 2-hexylidene-3-methylsuccinic acid 4-methyl ester (4) and an ophiobolane sesterterpene named halorosellinic acid (5), were isolated from culture broth of th...