Limited global diversity of the Plasmodium vivax merozoite surface protein 4 gene

• Main Authors: Chaturong Putaporntip, Somchai Jongwutiwes, Marcelo U. Ferreira, Hiroji Kanbara, Rachanee Udomsangpetch, Liwang Cui
• Other Authors: Chulalongkorn University
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/26985
• Institution: Mahidol University

Merozoite surface proteins (MSPs) of the malaria parasites are major candidates for vaccine development targeting asexual blood stages. However, the diverse antigenic repertoire of these antigens that induce strain-specific protective immunity in human is a major challenge for vaccine design and oft...