Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria: A prospective multi-centre individual patient data analysis

• Main Authors: Julien Zwang, Elizabeth A. Ashley, Corine Karema, Umberto D'Alessandro, Frank Smithuis, Grant Dorsey, Bart Janssens, Mayfong Mayxay, Paul Newton, Pratap Singhasivanon, Kasia Stepniewska, Nicholas J. White, François Nosten
• Other Authors: Shoklo Malaria Research Unit
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/27001
• Institution: Mahidol University

Background: The fixed dose antimalarial combination of dihydroartemisinin-piperaquine (DP) is a promising new artemisinin-based combination therapy (ACT). We present an individual patient data analysis of efficacy and tolerability in acute uncomplicated falciparum malaria, from seven published rando...