Peptide-morpholino conjugate: A promising therapeutic for duchenne muscular dystrophy

Steric-blocking oligos can correct reading frame errors or skip premature termination codons. For Duchenne muscular dystrophy (DMD), systemic administration of oligos produces limited delivery into muscle cells. Conjugation to a cell-penetrating peptide greatly enhances muscle uptake of morpholino o...

Full description

Saved in:
Bibliographic Details
Main Authors: Hong M. Moulton, Bo Wu, Natee Jearawiriyapaisarn, Peter Sazani, Qi Long Lu, Ryszard Kole
Other Authors: AVI BioPharma Incorporated
Format: Conference or Workshop Item
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/27085
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University