Peptide-morpholino conjugate: A promising therapeutic for duchenne muscular dystrophy
Steric-blocking oligos can correct reading frame errors or skip premature termination codons. For Duchenne muscular dystrophy (DMD), systemic administration of oligos produces limited delivery into muscle cells. Conjugation to a cell-penetrating peptide greatly enhances muscle uptake of morpholino o...
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Main Authors: | Hong M. Moulton, Bo Wu, Natee Jearawiriyapaisarn, Peter Sazani, Qi Long Lu, Ryszard Kole |
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Other Authors: | AVI BioPharma Incorporated |
Format: | Conference or Workshop Item |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/27085 |
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Institution: | Mahidol University |
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