Therapeutic potential of splice-switching oligonucleotides
Alternative splicing enables a single pre-messenger RNA transcript to yield multiple protein isoforms, making it a major contributor to the diversity of the proteome. While this process is essential for normal development, aberrations in alternative splicing are the cause of a multitude of human dis...
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Main Authors: | , , |
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Format: | Review |
Published: |
2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/27275 |
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Institution: | Mahidol University |