Plasmodium falciparum pfmdrl amplification, mefloquine resistance, and parasite fitness

Plasmodium falciparum pfmdrl amplification, mefloquine resistance, and parasite fitness

Mefloquine is widely used in combination with artemisinin derivatives for the treatment of falciparum malaria. Mefloquine resistance in Plasmodium falciparum has been related to increased copy numbers of multidrug-resistant gene 1 (pfmdrl). We studied the ex vivo dynamics of pfmdrl gene amplificatio...

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Bibliographic Details
Main Authors: Piyanuch Preechapornkul, Mallika Imwong, Kesinee Chotivanich, Wirichada Pongtavornpinyo, Arjen M. Dondorp, Nicholas P J Day, Nicholas J. White, Sasithon Pukrittayakamee
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Medicine
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/28131
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/28131

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