Estimation of the total parasite biomass in acute falciparum malaria from plasma PfHRP2

• Main Authors: Arjen M. Dondorp, Varunee Desakorn, Wirichada Pongtavornpinyo, Duangjai Sahassananda, Kamolrat Silamut, Kesinee Chotivanich, Paul N. Newton, Punnee Pitisuttithum, A. M. Smithyman, Nicholas J. White, Nicholas P.J. Day
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/16716

Background: In falciparum malaria sequestration of erythrocytes containing mature forms of Plasmodium falciparum in the microvasculature of vital organs is central to pathology, but quantitation of this hidden sequestered parasite load in vivo has not previously been possible. The peripheral blood p...