Enhanced susceptibility of nasal polyp tissues to avian and human influenza viruses

• Main Authors: Ornpreya Suptawiwat, Pongsakorn Tantilipikorn, Chompunuch Boonarkart, Jate Lumyongsatien, Mongkol Uiprasertkul, Pilaipan Puthavathana, Prasert Auewarakul
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/28439

Background: Influenza viruses bind and infect respiratory epithelial cells through sialic acid on cell surface. Differential preference to sialic acid types contributes to host- and tissue-tropism of avian and seasonal influenza viruses. Although the highly pathogenic avian influenza virus H5N1 can...