Pathogenesis of pulmonary Cryptococcus gattii infection: A rat model

• Main Authors: Mark B. Krockenberger, Richard Malik, Popchai Ngamskulrungroj, Luciana Trilles, Patricia Escandon, Susan Dowd, Chris Allen, Uwe Himmelreich, Paul J. Canfield, Tania C. Sorrell, Wieland Meyer
• Other Authors: The University of Sydney
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/28442
• Institution: Mahidol University

A model of pulmonary cryptococcosis in immunocompetent rats was developed to better understand the virulence of Cryptococcus gattii. Six isolates were studied, representing four molecular genotypes (VGI-MATα, VGIIa-MATα, VGIIa-MATa, VGIIb-MATα), obtained from Australia, Vancouver (Canada) and Colomb...