Development and optimization of micro/nanoporous osmotic pump tablets

• Main Authors: Siracha Tuntikulwattana, Ampol Mitrevej, Teerakiat Kerdcharoen, Desmond B. Williams, Nuttanan Sinchaipanid
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/28496

Micro/nanoporous osmotic pump tablets coated with cellulose acetate containing polyvinylpyrolidone (PVP) as pore formers were fabricated. Propranolol hydrochloride was used as a model drug in this study. Formulation optimization based on USP 31 requirements was conducted following a central composit...