p53 protects lung cancer cells against metabolic stress

• Main Authors: Chompunoot Sinthupibulyakit, Wanida Ittarat, William H. St. Clair, Daret K. St. Clair
• Other Authors: University of Kentucky College of Medicine
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/28587
• Institution: Mahidol University

The preferential use of aerobic glycolysis for energy production by cancer cells, a phenomenon known as the 'Warburg effect', is well recognized and is being considered for therapeutic applications. However, whether inhibition of glycolysis will be effective in all types of cancer is uncle...