Esterase activity of Bordetella pertussis CyaC-acyltransferase against synthetic substrates: Implications for catalytic mechanism in vivo
Adenylate cyclase-hemolysin toxin (CyaA) produced from the human respiratory tract pathogen Bordetella pertussis requires fatty-acyl modification by CyaC-acyltransferase to become an active toxin. Previously, the recombinant CyaA pore-forming (CyaA-PF) fragment expressed in Escherichia coli was show...
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Main Authors: | , , , , |
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Format: | Article |
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2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/28771 |
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Institution: | Mahidol University |