Esterase activity of Bordetella pertussis CyaC-acyltransferase against synthetic substrates: Implications for catalytic mechanism in vivo

Adenylate cyclase-hemolysin toxin (CyaA) produced from the human respiratory tract pathogen Bordetella pertussis requires fatty-acyl modification by CyaC-acyltransferase to become an active toxin. Previously, the recombinant CyaA pore-forming (CyaA-PF) fragment expressed in Escherichia coli was show...

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Bibliographic Details
Main Authors: Niramon Thamwiriyasati, Busaba Powthongchin, Jongrak Kittiworakarn, Gerd Katzenmeier, Chanan Angsuthanasombat
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/28771
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Institution: Mahidol University

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