1,5-Anhydroglucitol attenuates cytokine release and protects mice with type 2 diabetes from inflammatory reactions

• Main Authors: X. Meng, S. Tancharoen, K. I. Kawahara, Y. Nawa, S. Taniguchi, T. Hashiguchi, Ikuro Maruyama
• Other Authors: Kagoshima University Faculty of Medicine
• Format: Article
• Published: 2018
• Subjects: Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/29290
• Institution: Mahidol University

1,5-anhydrogIucitol (1,5-AG) decreases in diabetic patients and is used as a marker of glycemic control. Type 2 diabetic patients are susceptibile to lipopolysaccharides (LPS), which stimulate macrophages to release large quantities of tumor necrosis factor (TNF)-α and interleukin (IL)-6. This study...