Effect of genetic alterations of cytarabine-metabolizing enzymes in childhood acute lymphoblastic leukemia

Effect of genetic alterations of cytarabine-metabolizing enzymes in childhood acute lymphoblastic leukemia

BACKGROUND: Single nucleotide polymorphisms (SNPs) of deoxycytidine kinase (dCK) and cytidine deaminase (CDA) are known to alter their enzymatic activities, which affect the metabolism of cytarabine. Currently, treatment of childhood acute lymphoblastic leukemia (ALL) includes cytarabine, especially...

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Bibliographic Details
Main Authors: Chumphorn Banklaui, Sumalee Jindadamrongwech, Ruchchadol Sawangpanich, Suntaree Apibal, Suradej Hongeng, Karan Paisooksantivatana, Samart Pakakasama
Other Authors: Mahidol University
Format: Article
Published: 2018
Subjects:
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/29825
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/29825

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