Molecular correlates of high-level antifolate resistance in Rwandan children with Plasmodium falciparum malaria

Antifolate drugs have an important role in the treatment of malaria. Polymorphisms in the genes encoding the dihydrofolate reductase and dihydropteroate synthetase enzymes cause resistance to the antifol and sulfa drugs, respectively. Rwanda has the highest levels of antimalarial drug resistance in...

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Bibliographic Details
Main Authors: Corine Karema, Mallika Imwong, Caterina I. Fanello, Kasia Stepniewska, Aline Uwimana, Supatchara Nakeesathit, Arjen Dondorp, Nicholas P. Day, Nicholas J. White
Other Authors: National Malaria Control Programme
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/29871
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Institution: Mahidol University