Postcoital antifertility effect of piperine
The antifertility activity of piperine was investigated in pregnant mice when given by various routes of administration and at different periods of gestation. Piperine effectively inhibited implantation, produced abortion and delayed labor when it was given from day 2 through 5, day 8 through 12 and...
Saved in:
Main Authors: | , , |
---|---|
Other Authors: | |
Format: | Article |
Published: |
2018
|
Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/30398 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Mahidol University |
id |
th-mahidol.30398 |
---|---|
record_format |
dspace |
spelling |
th-mahidol.303982018-10-12T14:28:17Z Postcoital antifertility effect of piperine P. Piyachaturawat T. Glinsukon P. Peugvicha Mahidol University Medicine The antifertility activity of piperine was investigated in pregnant mice when given by various routes of administration and at different periods of gestation. Piperine effectively inhibited implantation, produced abortion and delayed labor when it was given from day 2 through 5, day 8 through 12 and day 15 until labor, respectively. At the same dose level which interrupts pregnancy, piperine did not affect the estrous cycle. Neither uterotropic, antiestrogenic nor antiprogestational property was observed. Additionally, piperine also inhibited uterine contraction both in vivo and in vitro. These results suggested that the antifertility activity of piperine did not operate through any hormonal actions or uterotonic activity. © 1983. 2018-10-12T07:28:17Z 2018-10-12T07:28:17Z 1982-01-01 Article Contraception. Vol.26, No.6 (1982), 625-633 10.1016/0010-7824(82)90137-8 00107824 2-s2.0-0020403742 https://repository.li.mahidol.ac.th/handle/123456789/30398 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0020403742&origin=inward |
institution |
Mahidol University |
building |
Mahidol University Library |
continent |
Asia |
country |
Thailand Thailand |
content_provider |
Mahidol University Library |
collection |
Mahidol University Institutional Repository |
topic |
Medicine |
spellingShingle |
Medicine P. Piyachaturawat T. Glinsukon P. Peugvicha Postcoital antifertility effect of piperine |
description |
The antifertility activity of piperine was investigated in pregnant mice when given by various routes of administration and at different periods of gestation. Piperine effectively inhibited implantation, produced abortion and delayed labor when it was given from day 2 through 5, day 8 through 12 and day 15 until labor, respectively. At the same dose level which interrupts pregnancy, piperine did not affect the estrous cycle. Neither uterotropic, antiestrogenic nor antiprogestational property was observed. Additionally, piperine also inhibited uterine contraction both in vivo and in vitro. These results suggested that the antifertility activity of piperine did not operate through any hormonal actions or uterotonic activity. © 1983. |
author2 |
Mahidol University |
author_facet |
Mahidol University P. Piyachaturawat T. Glinsukon P. Peugvicha |
format |
Article |
author |
P. Piyachaturawat T. Glinsukon P. Peugvicha |
author_sort |
P. Piyachaturawat |
title |
Postcoital antifertility effect of piperine |
title_short |
Postcoital antifertility effect of piperine |
title_full |
Postcoital antifertility effect of piperine |
title_fullStr |
Postcoital antifertility effect of piperine |
title_full_unstemmed |
Postcoital antifertility effect of piperine |
title_sort |
postcoital antifertility effect of piperine |
publishDate |
2018 |
url |
https://repository.li.mahidol.ac.th/handle/123456789/30398 |
_version_ |
1763493377631846400 |