Improvement of culture conditions for long‑term in vitro culture of Plasmodium vivax

• Main Authors: Wanlapa Roobsoong, Tharinjaroen, Chayada S, Nattawan Rachaphaew, Porpimon Chobson, Louis Schofield, Liwang Cui, Adams, John H, Jetsumon Sattabongkot
• Other Authors: Mahidol University. Faculty of Tropical Medicine. Mahidol Vivax Research Unit
• Format: Other
• Language: English
• Published: 2017
• Subjects: Open Access article; Plasmodium vivax; In vitro culture; Invasion assay; Membrane feeding assay; Culture medium; Reticulocytes
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/3081
• Institution: Mahidol University

Background: The study of the biology, transmission and pathogenesis of Plasmodium vivax is hindered due to the lack of a robustly propagating, continuous culture of this parasite. The current culture system for P. vivax parasites still suffered from consistency and difficulties in long-term mainte...