Nimbolide, a constituent of Azadirachta indica, inhibits Plasmodium falciparum in culture

The terpenoid lactone nimbolide, the structure of which has been unambiguously established, was found to inhibit Plasmodium falciparum in culture with a moderate potency. The EC50 against the parasite line K1 from Thailand was approximately 2.0 μM (0.95 μg/ml). The EC50 of crude aqueous extract of A...

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Bibliographic Details
Main Authors: S. Rochanakij, Y. Thebtaranonth, C. Yenjai, Y. Yuthavong
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/30820
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Institution: Mahidol University