Nimbolide, a constituent of Azadirachta indica, inhibits Plasmodium falciparum in culture
The terpenoid lactone nimbolide, the structure of which has been unambiguously established, was found to inhibit Plasmodium falciparum in culture with a moderate potency. The EC50 against the parasite line K1 from Thailand was approximately 2.0 μM (0.95 μg/ml). The EC50 of crude aqueous extract of A...
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Main Authors: | S. Rochanakij, Y. Thebtaranonth, C. Yenjai, Y. Yuthavong |
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Other Authors: | Mahidol University |
Format: | Article |
Published: |
2018
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/30820 |
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Institution: | Mahidol University |
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