Genetic Diversity and Lack of Artemisinin Selection Signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion

Genetic Diversity and Lack of Artemisinin Selection Signature on the Plasmodium falciparum ATP6 in the Greater Mekong Subregion

The recent detection of clinical Artemisinin (ART) resistance manifested as delayed parasite clearance in the Cambodia-Thailand border area raises a serious concern. The mechanism of ART resistance is not clear; but the P. falciparum sarco/endoplasmic reticulum Ca2+-ATPase (PfSERCA or PfATP6) has be...

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Bibliographic Details
Main Authors: Miao Miao, Zenglei Wang, Zhaoqing Yang, Lili Yuan, Daniel M. Parker, Chaturong Putaporntip, Somchai Jongwutiwes, Phonepadith Xangsayarath, Tiengkham Pongvongsa, Hazuhiko Moji, Trinh Dinh Tuong, Tomoko Abe, Shusuke Nakazawa, Myat Phone Kyaw, Guiyun Yan, Jeeraphat Sirichaisinthop, Jetsumon Sattabongkot, Jianbing Mu, Xin zhuan Su, Osamu Kaneko, Liwang Cui
Other Authors: Pennsylvania State University
Format: Article
Published: 2018
Subjects:
Agricultural and Biological Sciences
Biochemistry, Genetics and Molecular Biology
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31049
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Institution: Mahidol University

Internet

https://repository.li.mahidol.ac.th/handle/123456789/31049

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