Heat stabilization of blood spot samples for determination of metabolically unstable drug compounds

Background: Sample stability is critical for accurate analysis of drug compounds in biosamples. The use of additives to eradicate the enzymatic activity causing loss of these analytes has its limitations. Results: A novel technique for sample stabilization by rapid, high-temperature heating was used...

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Bibliographic Details
Main Authors: Daniel Blessborn, Karl Sköld, David Zeeberg, Karnrawee Kaewkhao, Olof Sköld, Martin Ahnoff
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31426
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Institution: Mahidol University