Diversity of the 47-kD HtrA nucleic acid and translated amino acid sequences from 17 recent human isolates of Orientia

Orientia tsutsugamushi, the etiologic agent of potentially fatal scrub typhus, is characterized by a high antigenic diversity, which complicates the development of a broadly protective vaccine. Efficacy studies in murine and nonhuman primate models demonstrated the DNA vaccine candidate pKarp47, bas...

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Bibliographic Details
Main Authors: Ju Jiang, Daniel H. Paris, Stuart D. Blacksell, Nuntipa Aukkanit, Paul N. Newton, Rattanaphone Phetsouvanh, Leonard Izzard, John Stenos, Stephen R. Graves, Nicholas P.J. Day, Allen L. Richards
Other Authors: Naval Medical Research Center
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31906
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Institution: Mahidol University