Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects

Floctafenine, a hydroxyquinoline derivative with analgesic properties, is widely used in Thailand and many other countries. The objectives of this study were to evaluate in Thai healthy volunteers: i) the inhibition of whole blood cyclooxygenase(COX)-2 and COX-1 activity by floctafenine and its meta...

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Main Authors: R. Maenthaisong, S. Tacconelli, P. Sritara, P. Del Boccio, L. Di Francesco, P. Sacchetta, N. Archararit, K. Aryurachai, Paola Patrignani, C. Suthisisang
Other Authors: University of G. d'Annunzio Chieti and Pescara
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31988
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Institution: Mahidol University