Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects

Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects

Floctafenine, a hydroxyquinoline derivative with analgesic properties, is widely used in Thailand and many other countries. The objectives of this study were to evaluate in Thai healthy volunteers: i) the inhibition of whole blood cyclooxygenase(COX)-2 and COX-1 activity by floctafenine and its meta...

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Main Authors: R. Maenthaisong, S. Tacconelli, P. Sritara, P. Del Boccio, L. Di Francesco, P. Sacchetta, N. Archararit, K. Aryurachai, Paola Patrignani, C. Suthisisang
Other Authors: University of G. d'Annunzio Chieti and Pescara
Format: Article
Published: 2018
Subjects:
Immunology and Microbiology
Medicine
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/31988
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/31988

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