Glycophorin C (CD236R) mediates vivax malaria parasite rosetting to normocytes

• Main Authors: Wenn Chyau Lee, Benoit Malleret, Yee Ling Lau, Marjorie Mauduit, Mun Yik Fong, Jee Sun Cho, Rossarin Suwanarusk, Rou Zhang, Letusa Albrecht, Fabio T M Costa, Peter Preiser, Rose McGready, Laurent Renia, Francois Nosten, Bruce Russell
• Other Authors: University of Malaya
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/33268
• Institution: Mahidol University

Rosetting phenomenon has been linked to malaria pathogenesis. Although rosetting occurs in all causes of human malaria, most data on this subject has been derived from Plasmodium falciparum. Here, we investigate the function and factors affecting rosette formation in Plasmodiumvivax. To achieve this...