Ablation of TrkB signalling in CCK neurons results in hypercortisolism and obesity

Ablation of TrkB signalling in CCK neurons results in hypercortisolism and obesity

Dysregulation of hypothalamic-pituitary-adrenal (HPA) axis activity leads to debilitating neuroendocrine or metabolic disorders such as Cushing's syndrome (CS). Glucocorticoids control HPA axis activity through negative feedback to the pituitary gland and the central nervous system (CNS). Howev...

Full description

Saved in:
Bibliographic Details
Main Authors: Mirjam Geibel, Sylvia Badurek, Jacqueline M. Horn, Chinnavuth Vatanashevanopakorn, Juraj Koudelka, Claudia M. Wunderlich, Hella S. Brönneke, F. Thomas Wunderlich, Liliana Minichiello
Other Authors: University of Oxford
Format: Article
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Chemistry
Physics and Astronomy
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/33287
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University

Internet

https://repository.li.mahidol.ac.th/handle/123456789/33287

Similar Items