The association between perchlorate and thiocyanate exposure and thyroid function in first-trimester pregnant Thai women

• Main Authors: Natthinee Charatcharoenwitthaya, Boonsong Ongphiphadhanakul, Elizabeth N. Pearce, Charintip Somprasit, Athita Chanthasenanont, Xuemei He, Laor Chailurkit, Lewis E. Braverman
• Other Authors: Faculty of Medicine, Thammasat University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/33482
• Institution: Mahidol University

Context: Thyroid hormone is critical for fetal neurodevelopment. Perchlorate and thiocyanate decrease thyroidal iodine uptake by competitively inhibiting the sodium/iodide symporter. It is clear that perchlorate and thiocyanate anions can influence thyroid function. However, as pollutants in the env...