Population pharmacokinetic assessment of the effect of food on piperaquine bioavailability in patients with uncomplicated malaria

• Main Authors: Joel Tarning, Niklas Lindegardh, Khin Maung Lwin, Anna Annerberg, Lily Kiricharoen, Elizabeth Ashley, Nicholas J. White, François Nosten, Nicholas P.J. Day
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/34727

Previously published literature reports various impacts of food on the oral bioavailability of piperaquine. The aim of this study was to use a population modeling approach to investigate the impact of concomitant intake of a small amount of food on piperaquine pharmacokinetics. This was an open, ran...