Phosphorylation of Ser283 enhances the stiffness of the tropomyosin head-to-tail overlap domain

• Main Authors: William Lehman, Greg Medlock, Xiaochuan Li, Worawit Suphamungmee, An Yue Tu, Anja Schmidtmann, Zoltán Ujfalusi, Stefan Fischer, Jeffrey R. Moore, Michael A. Geeves, Michael Regnier
• Other Authors: Boston University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/35479
• Institution: Mahidol University

© 2015 Elsevier Inc. The ends of coiled-coil tropomyosin molecules are joined together by nine to ten residue-long head-to-tail "overlapping domains". These short four-chained interconnections ensure formation of continuous tropomyosin cables that wrap around actin filaments. Molecular Dyn...