Selective disruption of heparin and antithrombin-mediated regulation of human factor IX

© 2015 International Society on Thrombosis and Haemostasis. Interaction with antithrombin and heparin regulates distribution, activity, and clearance of factor IXa (FIXa). Hemophilia B prophylaxis targets plasma FIX levels > 1% but neglects extravascular FIX, which colocalizes with antithrombin-h...

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Bibliographic Details
Main Authors: P. R. Westmark, P. Tanratana, J. P. Sheehan
Other Authors: University of Wisconsin Madison
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/36698
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Institution: Mahidol University