Selective disruption of heparin and antithrombin-mediated regulation of human factor IX

• المؤلفون الرئيسيون: P. R. Westmark, P. Tanratana, J. P. Sheehan
• مؤلفون آخرون: University of Wisconsin Madison
• التنسيق: مقال
• منشور في: 2018
• الموضوعات: Medicine
• الوصول للمادة أونلاين: https://repository.li.mahidol.ac.th/handle/123456789/36698

© 2015 International Society on Thrombosis and Haemostasis. Interaction with antithrombin and heparin regulates distribution, activity, and clearance of factor IXa (FIXa). Hemophilia B prophylaxis targets plasma FIX levels > 1% but neglects extravascular FIX, which colocalizes with antithrombin-h...