Development and characterization of bio-derived polyhydroxyalkanoate nanoparticles as a delivery system for hydrophobic photodynamic therapy agents

• Main Authors: Sasivimon Pramual, Apinya Assavanig, Magnus Bergkvist, Carl A. Batt, Panya Sunintaboon, Kriengsak Lirdprapamongkol, Jisnuson Svasti, Nuttawee Niamsiri
• Other Authors: Mahidol University
• Format: Article
• Published: 2018
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Engineering; Materials Science
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/43172

© 2015, Springer Science+Business Media New York. In this study, we developed and investigated nanoparticles of biologically-derived, biodegradable polyhydroxyalkanoates (PHAs) as carriers of a hydrophobic photosensitizer, 5,10,15,20-Tetrakis(4-hydroxy-phenyl)-21H, 23H-porphine (pTHPP) for photodyna...