Modulation of vaccine-induced CD4 T cell functional profiles by changes in components of HIV vaccine regimens in humans

• Main Authors: Franco Pissani, Bianca Schulte, Michael A. Eller, Bruce T. Schultz, Silvia Ratto-Kim, Mary Marovich, Prasert Thongcharoen, Somchai Sriplienchan, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Stefan Esser, Galit Alter, Merlin L. Robb, Jerome H. Kim, Nelson L. Michael, Hendrik Streeck
• Other Authors: International Vaccine Institute, Seoul
• Format: Article
• Published: 2019
• Subjects: Agricultural and Biological Sciences; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/44917
• Institution: Mahidol University

Copyright © 2018 American Society for Microbiology. All Rights Reserved. To date, six vaccine strategies have been evaluated in clinical trials for their efficacy at inducing protective immune responses against HIV infection. However, only the ALVAC-HIV/AIDSVAX B/E vaccine (RV144 trial) has demonstr...