Specificity and functional interplay between influenza virus PA-X and NS1 shutoff activity

• Main Authors: Chutikarn Chaimayo, Megan Dunagan, Tsuyoshi Hayashi, Netty Santoso, Toru Takimoto
• Other Authors: University of Rochester Medical Center
• Format: Article
• Published: 2019
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/45019
• Institution: Mahidol University

© 2018 Chaimayo et al. http://creativecommons.org/licenses/by/4.0/. Influenza A viruses modulate host antiviral responses to promote viral growth and pathogenicity. Through viral PA-X and NS1 proteins, the virus is capable of suppressing host protein synthesis, termed “host shutoff.” Although both p...