Dysregulated microRNA expression profiles in cholangiocarcinoma cell-derived exosomes

• Main Authors: Sarunya Kitdumrongthum, Chanatip Metheetrairut, Varodom Charoensawan, Puey Ounjai, Keatdamrong Janpipatkul, Wittaya Panvongsa, Jittima Weerachayaphorn, Pawinee Piyachaturawat, Arthit Chairoungdua
• Other Authors: Yale University School of Medicine
• Format: Article
• Published: 2019
• Subjects: Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/45038
• Institution: Mahidol University

© 2018 Elsevier Inc. Aim: Cholangiocarcinoma (CCA) is a malignant tumor of bile duct epithelial cells. The prognosis of CCA is poor due to lack of effective therapeutic targets and detection at an advanced stage. Exosomes are secreted nano-sized vesicles and contribute to the malignancy of several c...