Encoding Growth Factor Identity in the Temporal Dynamics of FOXO3 under the Combinatorial Control of ERK and AKT Kinases
© 2018 The Authors Extracellular growth factors signal to transcription factors via a limited number of cytoplasmic kinase cascades. It remains unclear how such cascades encode ligand identities and concentrations. In this paper, we use live-cell imaging and statistical modeling to study FOXO3, a tr...
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Main Authors: | , , , , , |
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Format: | Article |
Published: |
2019
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/45130 |
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Institution: | Mahidol University |