Encoding Growth Factor Identity in the Temporal Dynamics of FOXO3 under the Combinatorial Control of ERK and AKT Kinases
© 2018 The Authors Extracellular growth factors signal to transcription factors via a limited number of cytoplasmic kinase cascades. It remains unclear how such cascades encode ligand identities and concentrations. In this paper, we use live-cell imaging and statistical modeling to study FOXO3, a tr...
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Main Authors: | Somponnat Sampattavanich, Bernhard Steiert, Bernhard A. Kramer, Benjamin M. Gyori, John G. Albeck, Peter K. Sorger |
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Other Authors: | Universität Freiburg im Breisgau |
Format: | Article |
Published: |
2019
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/45130 |
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Institution: | Mahidol University |
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