Factor VII deficiency: Unveiling the cellular and molecular mechanisms underlying three model alterations of the enzyme catalytic domain

Factor VII deficiency: Unveiling the cellular and molecular mechanisms underlying three model alterations of the enzyme catalytic domain

© 2017 Elsevier B.V. Activated factor (F) VII is a vitamin K-dependent glycoprotein that initiates blood coagulation upon interaction with tissue factor. FVII deficiency is the most common of the rare congenital bleeding disorders. While the mutational pattern has been extensively characterized, the...

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Bibliographic Details
Main Authors: Maria Eugenia Chollet, Elisabeth Andersen, Ellen Skarpen, Christiane F. Myklebust, Christian Koehler, Jens Preben Morth, Ampaiwan Chuansumrit, Mirko Pinotti, Francesco Bernardi, Bernd Thiede, Per Morten Sandset, Grethe Skretting
Other Authors: Oslo University Hospital
Format: Article
Published: 2019
Subjects:
Biochemistry, Genetics and Molecular Biology
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/45228
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/45228

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