Factor VII deficiency: Unveiling the cellular and molecular mechanisms underlying three model alterations of the enzyme catalytic domain
© 2017 Elsevier B.V. Activated factor (F) VII is a vitamin K-dependent glycoprotein that initiates blood coagulation upon interaction with tissue factor. FVII deficiency is the most common of the rare congenital bleeding disorders. While the mutational pattern has been extensively characterized, the...
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Main Authors: | Maria Eugenia Chollet, Elisabeth Andersen, Ellen Skarpen, Christiane F. Myklebust, Christian Koehler, Jens Preben Morth, Ampaiwan Chuansumrit, Mirko Pinotti, Francesco Bernardi, Bernd Thiede, Per Morten Sandset, Grethe Skretting |
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Other Authors: | Oslo University Hospital |
Format: | Article |
Published: |
2019
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/45228 |
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Institution: | Mahidol University |
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